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I used to think creatine was just for men. Big, bulky guys, with shaker bottles that were probably left unwashed far too long inside their car. You know. The “gym bro” kinda type. Not for me; a 32-year-old woman who works out, eats well, and still feels more tired than she should. I thought I just needed more discipline. But it turns out, science only just started studying how creatine works in women's bodies. And after 13 hours down the research rabbit hole (you know how it is haha) here's what I found:
REASON number 1
Researchers at the University of North Carolina found that women produce creatine at rates roughly 20% lower than men, and eat around 30-40% less dietary creatine on average. Think of creatine as fuel for your muscles and your brain. Men start with a fuller tank. Women? Closer to a quarter full, sometimes event less. So we start lower, eat less of it, and then wonder why we're exhausted. Supplementing isn't adding something foreign. It's topping up something your body was already short on.
Reason 2:
Seventy to eighty percent less!!! That's not a small gap, that's a canyon. Research published in Nutrients found that women carry significantly lower creatine stores in their muscles compared to men. Creatine is what helps your body produce energy fast , during lifting, sprinting, any high-effort movement. When your stores are low, you fatigue faster, recover slower, and feel every rep more. This isn't a willpower problem. It's a biology problem with a very simple fix.
Reason 3:
This is where it gets interesting. Oestrogen and progesterone, the hormones that shift throughout your cycle, actually affect how your body processes creatine. Researchers found that creatine enzyme activity follows a similar pattern to oestrogen fluctuations. Meaning: how efficiently your body uses creatine changes depending on where you are in your cycle. There's also evidence that women with lower dietary creatine have a higher risk of irregular periods. Nobody told me creatine had anything to do with my hormones. The science is only just catching up.
REASON 4
I know what you're thinking. The 2021 review in Nutrients pulled together decades of research on creatine in women specifically and found consistent improvements in strength and exercise performance. What it DOESN'T do is make you look like a bodybuilder. Creatine helps your muscles produce energy more efficiently. More energy in your workouts means stronger, more toned look (exactly what you want girl). For me the shift showed up around week three. The weights that felt like a ceiling suddenly felt manageable. I wasn't more disciplined. I was just finally fuelled properly.
REASON 5
Up to 20% of your creatine is stored in your brain - and your brain uses it too. Research found that supplementation may improve mood and cognitive function in women by helping the brain maintain its energy levels. Clearer thinking. Less brain fog. Better mood when you need it most. This matters even more as we get older — post-menopausal research shows benefits in both muscle function and bone health. I noticed the brain difference before I even noticed the gym difference. That 3pm fog I thought was just life? Gone.
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